Probability & Statistics

A Positive Test

Prevalence 0.5 percent, no false negatives, 7 percent false positives. Bayes prices a positive stranger at 0.005 over 0.005 + 0.07 x 0.995, about 6.7 percent, the base-rate fallacy compressed into one fraction.

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A disease occurs with probability 0.5%0.5\% in the population. A test returns positive for sure if you have the disease, and gives a false positive 7%7\% of the time if you do not. A random stranger tests positive. What is the probability that the stranger has the disease?

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#Bayes with a rare disease

P(D+)=P(+D)P(D)P(+D)P(D)+P(+¬D)P(¬D)=10.00510.005+0.070.995.(1)\PP(D \mid +) = \frac{\PP(+ \mid D)\,\PP(D)}{\PP(+ \mid D)\,\PP(D) + \PP(+ \mid \neg D)\,\PP(\neg D)} = \frac{1 \cdot 0.005}{1 \cdot 0.005 + 0.07 \cdot 0.995}. \tag{1}

#Crunch the numbers

=0.0050.005+0.06965=0.0050.074650.067.(2)= \frac{0.005}{0.005 + 0.06965} = \frac{0.005}{0.07465} \approx 0.067. \tag{2}
truly sickfalse alarm
Out of ten thousand people, fifty carry the disease and all test positive, but seven percent of the 9950 healthy add about 697 false alarms. The genuinely sick are a thin sliver of all positives, so a positive stranger is sick only about 6.7 percent of the time.

#The healthy majority swamps it

The probability is about 6.7%6.7\%. Even a test that never misses a true case leaves a positive stranger far more likely healthy than sick, because the 7%7\% false positives drawn from the 99.5%99.5\% healthy majority swamp the tiny 0.5%0.5\% who are genuinely ill. This is the base-rate fallacy.